mRNA Nanoparticle Carrier Characterization

After meticulously mixing mRNA with the nanoparticle carrier, Abnova conducts thorough quality control (QC) testing to ensure the quality and effectiveness of the complex. Key physical properties, such as particle size, polydispersity index (PDI), zeta potential, particle concentration, and encapsulation efficiency can be efficiently measured to guide product design, optimize the production process, determine stability and release specifications. Precise size measurement provides insights into stability and immune response evasion. A low PDI ensures consistent performance across batches, while optimal zeta potential enhances colloidal stability. Accurate determination of particle concentration supports consistent dosing, and high encapsulation efficiency maximizes payload while minimizing waste.