SOD1 monoclonal antibody, clone 24
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Specifications
Product Description
Mouse monoclonal antibody raised against full length recombinant SOD1.
Immunogen
Recombinant protein corresponding to full length human SOD1.
Host
Mouse
Reactivity
Human
Specificity
It can expression in HeLa whole cell lysate.
Form
Liquid
Purification
Affinity purification
Isotype
IgG1
Recommend Usage
Western blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Citrate-Tris-HCl buffer, pH 7.0 (0.02% Proclin 300)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Cell lysate)
Western blot analysis of HeLa whole cell lystae with SOD1 monoclonal antibody, clone 24 (Cat # MAB9887) at 1:500 dilution.Enzyme-linked Immunoabsorbent Assay
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Gene Info — SOD1
Entrez GeneID
6647GeneBank Accession#
NM_000454.4Protein Accession#
NP_000445.1Gene Name
SOD1
Gene Alias
ALS, ALS1, IPOA, SOD, homodimer
Gene Description
superoxide dismutase 1, soluble
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq
Other Designations
Cu /Zn superoxide dismutase|Cu/Zn superoxide dismutase|SOD, soluble|indophenoloxidase A|superoxide dismutase, cystolic
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Interactomes
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Pathways
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Diseases
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